Grape Seed Extract effectively reduced hyper-pigmentation

Melasma is common in pregnant women, and those taking contraceptives or hormone replacement therapy (HRT). It is also prevalent in men and women of Native American descent (on the forearms) and in men and women of German/Russian Jewish descent (on the face). Melasma are dark, irregular patches often found on the upper cheek, nose, lips, upper lip, and forehead and normally develop over time and does not cause any other symptoms beyond this cosmetic discoloration.

In this one year study on 12 Japanese women it was shown that grape seed extract has a lightening effect on melasma and effectively reduced hyper-pigmentation and that final results were achieved after 6 months of intake.

In a study on guinea pigs, the oral intake of grapeseed extract showed to have a marked lightening effect on the skin where the skin had pigmentation induced by ultra violet rays - like those of the sun. In this study, a control was kept with some of the other guinea pigs being given vitamin C instead - but they did not show and reduced pigmentation - therefore - it can be concluded that it is not the antioxidant effect that resulted in the skin lightening, but was due to anther pathway.

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